David Letterman: Possible successors

The host of Comedy Central’s “The Daily Show With Jon Stewart,” Stewart is a political satirist and writer who got his start as a stand-up comedian. He hosted the 78th and 80th Academy Awards. He’s known for his sarcastic wit and biting criticisms of politics, politicians and even the news outlets that cover them.  (Kevork Djansezian / Getty Images)

Actress, comedian, best-selling author and host of “Chelsea Lately,” Handler is one of the “in” crowd of celebrities, without actually trying to be there. Her talk show brings on guests who may or may not already be friends, and she is not afraid to ask biting questions or revisit awkward situations. The former stand-up is known for that same biting comedy, but will throw herself, and her drinking, in for good effect.  (Genaro Molina / Los Angeles Times)

Conan O’Brien was initially tapped as a probable successor to David Letterman, but after hosting the “Late Night Show” for 16 years, he earned a great spot as host of NBC’s “The Tonight show,” until it was ripped away by network politics. The onetime “Saturday Night Live” writer has his own successful late-night talk show on TBS. He is known for his quirky, sometimes-physical comedy and observational humor.